Police received a call reporting a burglary at an address on Broad Walk in Wilmslow at 5.30pm on Monday, 20th September.
Officers attended to the property to find the house had been thoroughly searched by offender(s).
A police spokesperson said "The occupants were not in at the time the burglary took place and it is unclear at this stage what has been stolen.
"Officers have conducted house-to-house enquiries and the investigation remains ongoing. Anyone with any information is asked to contact Cheshire Constabulary via the website and quote IML 1089580."