Masked men threatened a member of staff at a Subway store and demanded that they opened the safe on Saturday, 6th January.
The robbery occurred at at approximately 7.50pm when two masked men entered the Subway store at Summerfield's Village Centre on Dean Row Road.
They entered the store via the main entrance and once inside they went into the staff area and threatened a member of staff, demanding that they opened the safe. The men then stole a quantity of cash from the safe before fleeing the scene.
Both of the suspects were described as wearing dark clothing.
Detective Sergeant Angela Coppock said: "Investigations in relation to this incident are currently in their early stages and we are following a number of lines of enquiry, including examining CCTV footage and forensics.
"As part of my enquiries I'm keen to hear from anyone who believes they have any information which could assist with our investigation.
"Summerfield's Village Centre is a busy shopping centre and I believe that there will have been a number of people present at the time of this incident that may hold vital information."
Anyone with any information in relation to the incident is asked to contact Cheshire Police on 101 quoting incident number 679 of 6 January 2018. Information can also be reported anonymously to Crimestoppers on 0800 555 111.
This is the second robbery at the Summerfield's Subway store in recent months. In September, a man threatened staff at the store with a knife and demanded that they handed over the cash from the till and safe.