The new Co-op on Waters Lane will be opened this week by former Manchester City and England football player, Mike Summerbee.
He will be joined by the Mayor of Cheshire East Council Olivia Hunter on Thursday, 24th November to open the new food store following a £415,000 investment.
Children from St Anne's Fulshaw Primary School will also be among the guests of honour helping to launch the new Co-op.
The retailer acquired the former M Local convenience store in August, after the company went into administration, safeguarding local jobs and creating up to eight new retail roles.
Suzi Moore, Store Manager, said: "We are delighted to have made such a significant investment in Wilmslow, to be opening the Co-op's newest food store is an exciting time for the whole team - our aim is to establish the store as a local hub and we are looking forward to serving the community."
Through the Co-op's new membership scheme local community groups can receive a 1% reward on purchases of Co-op own-branded products and services - community groups initially set to benefit include Wilmslow Animal Sanctuary, Hampers of Hope and Café Unity.
The Co-op will also appoint two Community Pioneers to work with charities, schools and voluntary organisations to contribute to local life.
Nick Crofts, President of the Co-op's National Member Council, said: "The Co-op is moving forward with a clear purpose and momentum. The return to our 'clover leaf' design logo – first used in the 1960's - aims to re-establish the Co-op as a centre for the community, and we want shoppers to know that they can become a co-owner and member of their Co-op.
"We are also giving back to the community. Our members have an opportunity to make a difference locally simply by using their membership card when they shop with us and raise much needed funding for organisations who contribute to improving local life."